Measuring Analytes in Maternal Archived Samples (MAMAS) – MAMAS 3

Analysis of persistent chemicals in blood collected from pregnant individuals in North Bay, San Francisco & Central Coast, and Southern Counties during prenatal screening

Drawing of a pregnant individual

The Measuring Analytes in Maternal Archived Samples (MAMAS) project is designed to evaluate chemical exposures of pregnant individuals across California. For the MAMAS project, Biomonitoring California is analyzing a subset of blood samples collected as part of prenatal screening conducted by California’s Genetic Disease Screening Program (GDSP).

Samples used in MAMAS came from counties across California and were analyzed in three phases: MAMAS 1, MAMAS 2, and MAMAS 3.

In MAMAS 3, samples collected by GDSP in three geographic regions (North Bay, San Francisco/Central Coast, and Southern Counties) in 2016-2017 were analyzed by our laboratories for persistent organic pollutants (POPs) (i.e., polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), and organochlorine pesticides) and perfluoroalkyl and polyfluoroalkyl substances (PFASs). Of the 300 samples analyzed, 204 samples (subsample 1) were analyzed for POPs only and a distinct subsample of 96 samples (subsample 2) were analyzed for PFASs only.

MAMAS project samples were selected to provide sufficiently large strata for comparison by race; summary statistics are therefore not necessarily reflective of the underlying population.

Project Type:

Laboratory collaboration

Project Status:

Ongoing

Participants:

300 pregnant individuals

Sample Collection Date:

to

Sample Collection Area:

Three geographic regions of California: North Bay, San Francisco/Central Coast, and Southern Counties

Project Map:

Map of California with three geographic regions shaded green: North Bay, San Francisco/Central Coast, and Southern Counties