California Childhood Leukemia Study (CCLS)

Lab Collaboration

Analysis of flame retardants and other persistent chemicals in blood samples from mothers of children with leukemia and mothers of children without leukemia

Logo shows three young bears in yellow color standing in a row holding hands, with the name of the study shown in blue

The California Childhood Leukemia Study (CCLS) is a population-based case-control study that seeks to identify genetic and environmental risk factors for childhood leukemia.  The study is conducted by researchers at the University of California, Berkeley, School of Public Health.

In a sub-study designed to evaluate the relationships between chemicals in house dust and chemicals in children’s and mothers’ blood, Biomonitoring California laboratories have analyzed polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), and organochlorine pesticides in serum samples from 48 mothers.

The CCLS is supported in part by the National Institute of Environmental Health Sciences (NIEHS), the National Cancer Institute (NCI), and the US Environmental Protection Agency.

Project Publications

Whitehead et al. (2015)

Whitehead TP, Crispo-Smith S, Park JS, Petreas MX, Rappaport SM, Metayer C (2015). Concentrations of persistent organic pollutants in California women's serum and residential dust.  Environmental Research 136:57-66. Link to abstract on PubMed (link is external)

Project Type: 

Laboratory collaboration

Project Status: 



48 Mothers

Sample Collection Date: 

2006 to 2007

Sample Collection Area: 

Northern and Central California, including the San Francisco Bay Area, Sacramento Valley, and San Joaquin Valley

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