Biomonitoring California Scientific Guidance Panel Meeting, March 2020

Meeting Date & Time: Wednesday, March 4, 2020 - 10:00am to 4:30pm
Sacramento, CA

CalEPA Building, Sierra Hearing Room, 1001 I Street, Sacramento


Biomonitoring California
Scientific Guidance Panel Meeting
CalEPA Building, Sierra Hearing Room, 1001 I Street, Sacramento, CA
March 4, 2020: 10:00 am – 4:30 pm

To access the webcast on the day of the meeting, follow instructions at:

 All times shown below are approximate and subject to change

Panel members participating remotely 
    Eunha Hoh, PhD, MSES, Hardy Tower #4, San Diego State University (SDSU), 5500 Campanile Drive, San Diego, CA
      Penelope (Jenny) Quintana, PhD, MPH, Hardy Tower #104, SDSU, 5500 Campanile Drive, San Diego, CA

Lauren Zeise, PhD, Director, Office of Environmental Health Hazard Assessment (OEHHA)

Overview of the Meeting
      Meg Schwarzman, MD, MPH, Chair, Scientific Guidance Panel (SGP)

Program Update (~10:10 am)
      Presentation:  Nerissa Wu, PhD, California Department of Public Health (CDPH)
      Panel Questions
      Public Comment
      Panel Discussion and Input

Overview: Quaternary Ammonium Compounds (QACs) as Potential Designated Chemicals (~11:05 am)
      Presentation:  Shoba Iyer, PhD, OEHHA
      Document: Potential Designated Chemicals: Quaternary Ammonium Compounds
      Background: Preliminary Screening of Quaternary Ammonium Compounds
      Panel and Audience Questions

Reproductive and Developmental Toxicity of Selected QACs: A Chemical Detective Story (~11:35 am)
      Presentation:  Terry Hrubec, DVM, PhD, Professor of Anatomy and Embryology, Edward Via College of
        Osteopathic Medicine - Virginia
      Panel and Audience Questions

Lunch (~12:25 pm)

Reviewing QACs for Biomonitoring: Metabolism, Analytical Considerations, and Effects on
  Cholesterol Homeostasis (~1:35 pm)
      Presentation:  Libin Xu, PhD, Assistant Professor, Department of Medicinal Chemistry,
        School of Pharmacy, University of Washington
      Panel and Audience Questions

Discussion: Quaternary Ammonium Compounds as Potential Designated Chemicals (~2:25 pm)
      Guest Discussant Remarks
            Presentation: Robert Harrison, MD, MPH, Occupational Health Surveillance and Evaluation Program, CDPH
            Comments from the Work-Related Asthma Prevention Program, CDPH
      Panel and Audience Discussion
            Public comment presentation:  Keith Hostetler, PhD, on behalf of the ADBAC and DDAC Issues Steering Committees 
            Public comment presentation: Thomas Osimitz, PhD, DABT, on behalf of the Quat Residue Group

Break (~3:20 pm)

Panel Recommendation: Quaternary Ammonium Compounds as Potential Designated
Chemicals (~3:35 pm)
      Presentation: Options for the Panel, OEHHA
      Public Comment
            Comments from the Quat Residue Group 
      Panel Recommendation

Open Public Comment (~4:20 pm)

Wrap-up and Adjournment (by 4:30 pm)


Meeting Participation and Comment

The order of items on the agenda is subject to change at the discretion of the Chair.

Members of the public and representatives of organizations are invited to attend and participate in the SGP meeting. To ensure that the meeting proceeds on schedule and all commenters have the opportunity to speak, public comments may be subject to time limits. If necessary, the time allotted for public comments will be divided equally among all the individuals wishing to speak. Comments on an agenda item can also be sent to

If you have materials relevant to an agenda topic that you would like to submit, please send an electronic copy to or by mail to Biomonitoring California (c/o OEHHA, 1515 Clay St., 16th Floor, Oakland, CA 94612). If you are unable to send the materials in advance, please bring 12 paper copies and one electronic copy of the materials to the meeting. Relevant materials will be made available to the SGP.

Biomonitoring California complies with the Americans with Disabilities Act (ADA) by ensuring that the facilities are accessible to persons with disabilities, and by providing this notice and information in alternative formats when requested. If you have special accommodation or language needs, please contact the Program by telephone at (510) 622‑3149 or by e-mail at TTY/TDD/Speech-to-Speech users may dial 7-1-1 for the California Relay Service. It is requested, but not required, that you contact us at least five days before the meeting so we can ensure that the necessary staff or equipment will be available for you at the meeting.

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