Biomonitoring California Scientific Guidance Panel Meeting, March 2020

Meeting Date & Time: Wednesday, March 4, 2020 - 10:00am to 4:30pm
Location:
Sacramento, CA

CalEPA Building, Sierra Hearing Room, 1001 I Street, Sacramento(link is external)

Agenda

Biomonitoring California
Scientific Guidance Panel Meeting
March 4, 2020: 10:00 am – 4:30 pm

CalEPA Building, Sierra Hearing Room, 1001 I Street, Sacramento, CA

 All times shown below are approximate and subject to change

Panel members participating remotely
      Eunha Hoh, PhD, MSES, Hardy Tower #4, San Diego State University (SDSU), 5500 Campanile Drive, San Diego, CA
      Penelope (Jenny) Quintana, PhD, MPH, Hardy Tower #104, SDSU, 5500 Campanile Drive, San Diego, CA

 Welcome
     
Lauren Zeise, PhD, Director, Office of Environmental Health Hazard Assessment (OEHHA)

Overview of the Meeting
      Meg Schwarzman, MD, MPH, Chair, Scientific Guidance Panel (SGP)

Program Update (~10:10 am)
      Presentation:  Nerissa Wu, PhD, California Department of Public Health (CDPH)
      Panel Questions
      Public Comment
      Panel Discussion and Input

Overview: Quaternary Ammonium Compounds (QACs) as Potential Designated Chemicals (~11:05 am)
      Presentation:  Shoba Iyer, PhD, OEHHA
      Document: Potential Designated Chemicals: Quaternary Ammonium Compounds
      Background: Preliminary Screening of Quaternary Ammonium Compounds
      Panel and Audience Questions

Reproductive and Developmental Toxicity of Selected QACs: A Chemical Detective Story (~11:35 am)
      Presentation:  Terry Hrubec, DVM, PhD, Professor of Anatomy and Embryology, Edward Via College of
        Osteopathic Medicine - Virginia
      Panel and Audience Questions

Lunch (~12:25 pm)

Reviewing QACs for Biomonitoring: Metabolism, Analytical Considerations, and Effects on
  Cholesterol Homeostasis (~1:35 pm)
      Presentation:  Libin Xu, PhD, Assistant Professor, Department of Medicinal Chemistry,
        School of Pharmacy, University of Washington
      Panel and Audience Questions

Discussion: Quaternary Ammonium Compounds as Potential Designated Chemicals (~2:25 pm)
      Guest Discussant Remarks
            Presentation: Robert Harrison, MD, MPH, Occupational Health Surveillance and Evaluation Program, CDPH
            Comments from the Work-Related Asthma Prevention Program, CDPH
      Panel and Audience Discussion
            Public comment presentation:  Keith Hostetler, PhD, on behalf of the ADBAC and DDAC Issues Steering Committees 
            Public comment presentation: Thomas Osimitz, PhD, DABT, on behalf of the Quat Residue Group

Break (~3:20 pm)

Panel Recommendation: Quaternary Ammonium Compounds as Potential Designated
 
Chemicals (~3:35 pm)
      Presentation: Options for the Panel, OEHHA
      Public Comment
            Comments from the Quat Residue Group 
      Panel Recommendation

Open Public Comment (~4:20 pm)

Wrap-up and Adjournment (by 4:30 pm)