Biomonitoring California Scientific Guidance Panel Meeting, March 2021

Meeting Date & Time: Monday, March 8, 2021 - 10:00am to 4:30pm


Biomonitoring California
Scientific Guidance Panel Meeting
March 8, 2021: 10:00 am – 4:30 pm

This meeting will be held by webinar; please join by 9:55 am.
To access the webinar, follow these instructions
All times shown below are approximate and subject to change.


Logistics (~9:55 am)
        Stephanie Jarmul, MPH, Office of Environmental Health Hazard Assessment (OEHHA

Welcome (~10:00 am)
        Lauren Zeise, PhD, Director, OEHHA

Overview of the Meeting (~10:05 am)
        Meg Schwarzman, MD, MPH, Chair, Scientific Guidance Panel (SGP)

Program Update and Options for Statewide Surveillance (~10:10 am)
        Presentation: Nerissa Wu, PhD, California Department of Public Health
        Panel and Audience Questions

Introduction: Quaternary Ammonium Compounds (QACs) as Potential Priority Chemicals (~11:15 am)
        Document: Potential Priority Chemicals: Quaternary Ammonium Compounds
        Background Materials:
              Potential Designated Chemicals: Quaternary Ammonium Compounds 
              Preliminary Screening of Quaternary Ammonium Compounds 
        Introductory Presentation: Shoba Iyer, PhD, OEHHA
        Panel and Audience Questions

QACs: Detection in the Environment and Degradation Processes (~11:35 am)
        Presentation: Bill Arnold, PhD, Department of Civil, Environmental, and Geo‑ Engineering, University of Minnesota
        Panel and Audience Questions

Lunch (~12:15 pm)

Increased Human Exposure to QACs during the COVID-19 Pandemic (~1:15 pm)
        Presentation: Amina Salamova, PhD, O’Neill School of Public and Environmental Affairs, Indiana University
        Panel and Audience Questions

Analytical Methods for Measuring QACs in Biomonitoring Studies (~1:55 pm)
        Presentation: Libin Xu, PhD, Department of Medicinal Chemistry, School of Pharmacy, University of Washington
        Panel and Audience Questions

Break (~2:35 pm)

Evaluating the Safety of Quaternary Ammonium Compounds (QACs) (~2:50 pm)
        Presentation: Keith Hostetler, PhD, Trinity Consultants and John DeSesso, PhD, Exponent, Inc
        Panel and Audience Questions

 Quaternary Ammonium Compounds as Potential Priority Chemicals (~3:30 pm)
        Overview of Potential Priority Chemicals Document on QACs: Shoba Iyer, PhD, OEHHA
        Panel Questions
        Public Comment
              ADBAC Issues Steering Committee Comments on Analytical Methodology for QACs
              Women's Voices for the Earth Comments on QAC Exposures to Vulnerable Populations
              Women's Voices for the Earth Comments on FDA Evaluation of ADBAC Data Gaps 
        Additional Public Comment (received after March 8, 2021) 
              Hostetler KA, Fisher LC, Burruss BL (2021). Prenatal developmental toxicity of alkyl dimethyl benzyl ammonium
                  chloride and didecyl dimethyl ammonium chloride in CD rats and New Zealand White rabbits. Birth Defects
                  Res, 21 March 2021, doi: 10.1002/bdr2.1889. Epub ahead of print.
              Teratology Working Group (2021). Status Report on the Systematic Review of Quaternary Ammonium Disinfectant
                  Compounds for Developmental and Reproductive Toxicity.
        Panel Recommendation

Open Public Comment (~4:20 pm)

Wrap-up and Adjournment (~4:30 pm)


Webinar Instructions

This meeting will be held via GoToWebinar. Please be sure to join the webinar at least 5 minutes before the 10:00 am meeting start time. You can register as an attendee at this link:

To register, you will be required to provide a valid email address and a name. Note that you do not have to enter your actual name; for example, you could instead use initials. After registering, you will receive a confirmation email containing information about joining the webinar.

If you are a speaker or SGP member, please do not register using this link. You will receive your own link for joining the webinar. 

Meeting Participation and Comment

The order of items on the agenda is subject to change at the discretion of the Chair.

Members of the public and representatives of organizations are invited to participate in the SGP meeting via the webinar. To ensure that the meeting proceeds on schedule and all commenters have the opportunity to speak, public comments may be subject to time limits. Comments on an agenda item can be submitted through the webinar platform during the meeting, or sent to

If you have written materials about an agenda item that you would like to submit, please send an electronic copy to Relevant materials will be distributed to the SGP.

Biomonitoring California complies with the Americans with Disabilities Act (ADA) by ensuring that the facilities are accessible to persons with disabilities, and by providing this notice and information in alternative formats when requested. If you have special accommodation or language needs, please contact the program by calling (510) 622‑3149 or by sending an e-mail to TTY/TDD/Speech-to-Speech users may dial 7-1-1 for the California Relay Service. It is requested, but not required, that you contact us at least five days before the meeting so we can ensure that the necessary staff or equipment will be available for you at the meeting.

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