Biomonitoring California Webinar on Manganese PBPK Modeling, June 2011

Meeting Date & Time: Tuesday, June 14, 2011 - 10:00am to 12:00pm


Biomonitoring California will hold a webinar from 10 am to 12 noon on Tuesday, June 14, 2011.  The webinar will include a presentation and discussion on using physiologically based pharmacokinetic modeling to understand how exposures to manganese relate to levels in the human body.  More details on the webinar and how to register are provided below.

The Manganese Interest Group (MIG) submitted comments for the discussion of manganese as a potential designated chemical for Biomonitoring California at the program’s November 2010 Scientific Guidance Panel meeting.  MIG’s comments included slides from Dr. Harvey Clewell, Director of the Center for Human Health Assessment at The Hamner Institutes for Health Sciences. 

The Hamner Institutes developed a physiologically based pharmacokinetic (PBPK) model to explore the relationship between human tissue levels of manganese and intake of the metal through various routes such as the diet or environmental exposures in air.  At the June 14 webinar, Dr. Clewell will give a presentation on: 

“Application of PBPK modeling to evaluate data on human exposures to manganese, a toxic but essential metal.” 

Members of the audience can submit questions via email to during the webinar.  Questions will be read aloud after the presentation.  To download the slides for the June 14 presentation, follow this link

Space at the webinar is limited.  Please register as soon as possible at this link:  After registering you will receive a confirmation email containing information about joining the webinar. Please make sure to sign in at least 15 minutes before the webinar.  To hear the audio portion of the webinar, dial the teleconference line at (888)622-5357 and enter the access code of 593049.  Once you dial in, please mute your phone line.
System Requirements to join the webinar:

PC-based attendees
Required: Windows® 7, Vista, XP or 2003 Server

Macintosh®-based attendees
Required: Mac OS® X 10.4.11 (Tiger®) or newer

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